Situated within Rifle's original townsite, this well-appointed commercial property offers an excellent opportunity for medical, wellness, or professional office users seeking a centrally located and highly functional space. Zoned Special Purpose Land - Mixed Use and currently configured as a medical wellness practice, the 1,880-square-foot interior is thoughtfully designed for clinical or office operations, featuring four private treatment or exam rooms, two bathrooms, a private bedroom with a full ensuite bath ideal for on-call use or live-work flexibility, and a staff break room with a full kitchen. Extensive upgrades completed since 2023 enhance functionality, comfort, and overall presentation. The property also includes three dedicated off-street parking spaces at the rear, convenient street parking along the front, and a fully fenced backyard-an uncommon feature providing outdoor privacy for staff or specialized client services. Located in the heart of downtown Rifle and close to local amenities, the building blends historic character with modern improvements, making it well-suited for a range of professional, medical, or wellness uses and an attractive option for both owner-users and investors.